Venue: Murrayfield Date: Saturday, 18 March Kick-off: 12:30 GMT
Scotland have made two changes to the squad that lost badly to England last weekend. Lock Richie Gray misses out with a Hamstring injury so Grant Gilchrist comes in. And Ross Ford is preferred to Fraser Brown at Hooker.
Italy make four changes, Tommaso Benvenuti, Maxime Mbanda, George Biagi, Ornel Gega come in as Italy push to gain their first and only victory of this years Six Nations having been unable to avoid the Wooden Spoon.
Scotland: 15-Hogg; 14-Seymour, 13-Jones, 12-Dunbar, 11-Visser; 10-Russell, 9-Price; 1-Reid, 2-Ford, 3-Fagerson; 4-G Gilchrist, 5-J Gray; 6-Barclay (captain), 7-Watson, 8-Wilson.
Replacements: 16-Brown, 17-Berghan, 18-Du Preez, 19-Weir, 20-Dell, 21-Swinson, 22-Pyrgos, 23-Scott.
Italy: 15-Padovani; 14-Esposito, 13-Benvenuti, 12-McLean, 11-Venditti; 10-Canna, 9-Gori; 1-Lovotti, 2-Gega, 3-Cittadini, 4-Fuser, 5-Biagi, 6-Mbanda, 7-Steyn, 8-Parisse.
Replacements: 16-Ghiraldini, 17-Panico, 18-Chistolini, 19-Van Schalkwyk, 20-Ruzza, 21-Minto, 22-Violi, 23-Sperandio.
Scotland have won six of their past seven games against Italy. However, Italy beat Scotland on their most recent visit to Murrayfield in 2015.
Referee: Pascal Gauzere (France)
Touch judges: Nigel Owens (Wales) & Luke Pearce (England)
TMO: Marius Jonker (South Africa)